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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF6 All Species: 15.15
Human Site: Y650 Identified Species: 27.78
UniProt: Q6ZMV9 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZMV9 NP_659464.3 814 92569 Y650 L E E E K R R Y K T M F T R L
Chimpanzee Pan troglodytes XP_518451 814 92867 Y650 L E E E K R R Y K T M F T R L
Rhesus Macaque Macaca mulatta XP_001117160 818 92984 Y654 L E E E K R R Y K T M F T R L
Dog Lupus familis XP_538903 838 94815 Y649 L E E E K R R Y K T M F T H L
Cat Felis silvestris
Mouse Mus musculus Q9WV04 790 89924 A610 L N E R K K R A S E T T Q R I
Rat Rattus norvegicus Q7TSP2 1385 159522 K1042 E V D I L E L K E T L R L R I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q91785 1388 159123 I1049 I E E Q E K Q I E E L R E C L
Zebra Danio Brachydanio rerio NP_001070899 667 75528 Q526 F E E K I L T Q I E E E K K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394791 753 86748 T609 I E R K T S E T N D D E T N Q
Nematode Worm Caenorhab. elegans P46873 699 78760 T558 Q P I I K K D T N Y S N V D R
Sea Urchin Strong. purpuratus P46872 699 78679 V558 L M Q A K S E V A D M Q A E H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FZ06 919 100869 V653 G N A E K P P V A R L F E Q V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 H654 L E A L Q Q E H E E L L S R N
Conservation
Percent
Protein Identity: 100 97.4 96.6 78.8 N.A. 27.7 20.7 N.A. N.A. N.A. 21.9 50.3 N.A. N.A. 35.1 26 27.2
Protein Similarity: 100 98.6 97.4 83.8 N.A. 49 36 N.A. N.A. N.A. 36.8 63.7 N.A. N.A. 53 46.1 46.1
P-Site Identity: 100 100 100 93.3 N.A. 33.3 13.3 N.A. N.A. N.A. 20 13.3 N.A. N.A. 13.3 6.6 20
P-Site Similarity: 100 100 100 93.3 N.A. 46.6 40 N.A. N.A. N.A. 66.6 26.6 N.A. N.A. 26.6 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. 24.3
Protein Similarity: N.A. N.A. N.A. 42 N.A. 44.2
P-Site Identity: N.A. N.A. N.A. 20 N.A. 20
P-Site Similarity: N.A. N.A. N.A. 40 N.A. 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 8 0 0 0 8 16 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 8 0 0 0 8 0 0 16 8 0 0 8 0 % D
% Glu: 8 62 54 39 8 8 24 0 24 31 8 16 16 8 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 39 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 8 % H
% Ile: 16 0 8 16 8 0 0 8 8 0 0 0 0 0 16 % I
% Lys: 0 0 0 16 62 24 0 8 31 0 0 0 8 8 0 % K
% Leu: 54 0 0 8 8 8 8 0 0 0 31 8 8 0 39 % L
% Met: 0 8 0 0 0 0 0 0 0 0 39 0 0 0 0 % M
% Asn: 0 16 0 0 0 0 0 0 16 0 0 8 0 8 16 % N
% Pro: 0 8 0 0 0 8 8 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 8 8 8 8 8 8 0 0 0 8 8 8 8 % Q
% Arg: 0 0 8 8 0 31 39 0 0 8 0 16 0 47 8 % R
% Ser: 0 0 0 0 0 16 0 0 8 0 8 0 8 0 0 % S
% Thr: 0 0 0 0 8 0 8 16 0 39 8 8 39 0 0 % T
% Val: 0 8 0 0 0 0 0 16 0 0 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 31 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _